ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

May 9, 2013 Posted By: Leave a comment
Thomas Gaj, Charles A. Gersbach, Carlos F. Barbas.
• ZFNs, TALENs, and CRISPR/Cas-based RNA-guided DNA endonucleases are programmable site-specific nucleases.
• Site-specific nucleases induce DNA DSBs that stimulate N....
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