Ligand-targeted liposome design: challenges and fundamental considerations

Gavin T. Noble, Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, Basar Bilgicer.
• Ligand-targeted-liposomes (LTLs) enhance tumor targeting and intracellular uptake.
• However, LTL efficacy is hindered by several secondary biological effects.
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