Joerg Mampel, Joerg Martin Buescher, Guido Meurer, Juergen Eck. In the past decade, systems biology has revealed great metabolic and regulatory complexity even in seemingly simple microbial systems. Metabolic engineering aims to control this complexity in orde….
James M. Clomburg, Ramon Gonzalez. Highlights► Glycerol is an abundant and inexpensive carbon source generated as a by-product of biofuel production. ► High degree of reduction of glycerol enables increased yields of fuels and redu….
Abhinav A. Shukla, Uwe Gottschalk. Highlights► Single-use disposable technologies in the manufacturing of biopharmaceuticals ► Advantages and limitations of single-use manufacturing ► Single-use systems for protein drug substance p….
Jim C. Philp, Ken Guy, Rachael J. Ritchie. Any major change to the energy order is certain to provoke both positive and negative societal responses. The current wave of biofuels development ignited controversies that have re-shaped the thi….
Mohammad J. Hajipour, Katharina M. Fromm, Ali Akbar Ashkarran, Dorleta Jimenez de Aberasturi, Idoia Ruiz de Larramendi, Teofilo Rojo, Vahid Serpooshan, Wolfgang J. Parak, Morteza Mahmoudi.
Abdu I. Alayash, Christian Brix Folsted Andersen, Søren Kragh Moestrup, Leif Bülow. Hemoglobin (Hb) is one of the most studied proteins. However, oxidative toxicity associated with free Hb in circulation and its contribution to inflammation and complications of transfusion have … Continue reading
Jason Dictenberg. Recently RNA localization has been appreciated as an essential post-transcriptional mechanism to program local proteome composition and function. Although RNA has been visualized using diverse tec….
Tyrone Wells, Arthur J. Ragauskas. The β-ketoadipate pathway (β-KAP) is an enzyme-mediated aryl-ring degradation sequence employed by a wide selection of soil bacteria and fungi to reconcile the conversion of many hazardous aromati….
Christopher Hughes, Jeroen Krijgsveld. Two of the primary responses in a cell when perturbed are modulation of the dynamics of its constituent gene expression and protein abundance to restore steady-state homeostasis. To obtain a detai….